Tumor-infiltrating neutrophils can have either pro-tumoral potential or anti-tumoral potential. Physical contact between heterogeneous neutrophils and tumor cells in the tumor microenvironment is now shown to facilitate the malignant progression of breast cancer.
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Fig. 1: Heterogeneous neutrophils physically interact with tumor cells and promote breast carcinoma.
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Institute of Experimental Pathology (ExPat), Centre for Molecular Biology of Inflammation (ZMBE), University of Münster, Münster, Germany
Claudia Tulotta & Oliver Soehnlein
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Claudia Tulotta
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2. Oliver Soehnlein
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Tulotta, C., Soehnlein, O. Neutrophils take their PICk to promote breast cancer. Nat Cancer (2025). https://doi.org/10.1038/s43018-025-00925-2
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Published:12 March 2025
DOI:https://doi.org/10.1038/s43018-025-00925-2
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