Luka Doncic notched a triple-double with 22 points, 12 rebounds and 12 assists, but it wasn't enough as Los Angeles fell 111-108 in Brooklyn.
Playing without LeBron James, Max Christie and Dorian Finney-Smith, the Lakers couldn't muster the firepower to hand the Nets their eighth straight loss.
Noah Clowney paced Brooklyn with 19 points, Keon Johnson and Cam Johnson added 18.
The Nets snapped the skid, but there's no rest for the wicked as they travel to Cleveland to take on the Cavaliers on Tuesday.