Deepening our understanding of ‘Forever Chemicals’
Per- and polyfluoroalkyl substances (PFAS or 'Forever Chemicals') are an environmental and food-borne burden worldwide. PFAS are is a significant environmental and food contaminant. Of the 100’s of PFAS, there are two that have been studied in greater detail, perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS). The National Cancer Institute has classified these agents as potential carcinogens.
The intent of this Collection is to highlight data from different areas to establish a foundation for the role of PFAS in the development of cancer. This evidence would include in vivo, in vitro, and molecular studies of PFAS agents alone and in combination with other environmental pollutants or genetic mutations.
The importance of digging deeper
PFAS have been classified as harmful to human health and carcinogens (PFOA) and possible carcinogens (PFOS) that increase the risk of cancers of the testes, kidneys and thyroid, as well as affecting hormonal function and fertility.
Increasing our knowledge in these areas allows greater understanding of the impact of these substances, and allows further dissection of their role in cancer development.
This Collection supports and amplifies research directly related to the United Nation's Sustainable Development Goal 3 (SDG 3) – Good Health and Well-being for all.
How can this collection help?
Our Top Collections like this one aim to support and promote high-quality science. They are led by Guest Editors who are experts in their fields, and supported by a dedicated team of Commissioning Editors, Managing Editors and In-House Editors at Springer Nature. Collection articles typically see higher citations, downloads, and Altmetric scores, and provide a one-stop-shop on a cutting-edge topic of interest.
Championing the exploration of ‘Forever Chemicals’
Dr. David R Wallace is presently a full professor in Oklahoma State University Center for Health Sciences, USA. His research focuses on role of environmental toxicants and cancer.As a Guest Editor for Discover Toxicology, he is keen to see the impact of “Forever Chemicals” on cancer development highlighted on a global scale.
How can I submit my paper?
Visit the Collection page to find out more about this collection and submit your article.