UN's humanitarian agency OCHA said cracks and surface distortions on the main highway from Yangon (largest city) to Nay Pyi Taw (capital) to Mandalay have severely disrupted transport.
Trauma kits, blood bags, anesthetics, essential medicines, tents for health workers, etc, are in short supply.
A rescue team in Mandalay's Kyaukse district pulled out several people trapped under the debris of a private school.
But many victims- students, teachers, and school staff were found dead when they arrived.