The Premier League returns with outstanding matchday 21 set to be cleared across eight centres on Tuesday April 1 and Wednesday April 2, 2025.
The midweek slate features several compelling fixtures, including the Bono derby involving Young Apostles and Aduana FC as well as the Western derby between Medeama and Basake Holy Stars.
Second-placed **Gold Stars FC** host **Heart of Lions** at the Duns park in Bibiani on Tuesday April 1 seeking to keep the chase on leaders Asante Kotoko.
Medeama entertain neighbours Basake Holy Stars at the TnA Stadium in Tarkwa on Tuesday, hoping for a win to keep their Premier League title ambition on course.
The remaining six matches will take place on Wednesday April 2, 2025.
**Hearts of Oak** take on **Nations FC** at the Accra Sports Stadium while league leaders **Asante Kotoko** host **Berekum Chelsea** at the Baba Yara Stadium in Kumasi on Wednesday.
**Karela United** host struggling **Legon Cities** at the Aliu Mahama Sports Stadium while Aduana FC entertain Young Apostles in the Bono derby at the Nana Agyemang Badu I park.
**Vision FC** will be desperate to return to winning ways when they host defending champions **FC Samartex 1996** at the Nii Adjei Kraku II Sports Complex in Tema.
Rejuvenated **Dreams FC** battle **Bechem United** at the Tuba Astro turf on Wednesday April 2, 2025.
