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Long-term air pollution exposure linked to higher osteoporosis risk in cancer survivors

Korean medical researchers have published the world's first study showing that long-term exposure to air pollution increases the risk of osteoporosis in cancer survivors.

The National Cancer Center announced Monday that a research team found long-term exposure to fine particulate matter increases osteoporosis risk in female cancer survivors by more than 25 percent.

The study was led by Hwang Ju-yeon, a researcher at the National Cancer Center's Data Integration Team; Kim Hyun, a researcher at Sungkyunkwan University's School of Social Medicine; Kim Hyun-jin, head of the National Cancer Data Integration Team at the National Cancer Center; and Kim Ki-ju, a professor at Sungkyunkwan University's School of Social Medicine.

The National Cancer Center announced that a research team -- led by Hwang Ju-yeon, a researcher at the National Cancer Center's Data Integration Team, Kim Kyung-hyun, a researcher at Sungkyunkwan University's School of Social Medicine, Kim Hyun-jin, head of the National Cancer Data Integration Team at the National Cancer Center, and Kim Ki-ju, a professor at Sungkyunkwan University's School of Social Medicine -- has published the world's first study showing that exposure to air pollution increases the risk of osteoporosis in cancer survivors. (Courtesy of National Cancer Center)

The National Cancer Center announced that a research team -- led by Hwang Ju-yeon, a researcher at the National Cancer Center's Data Integration Team, Kim Kyung-hyun, a researcher at Sungkyunkwan University's School of Social Medicine, Kim Hyun-jin, head of the National Cancer Data Integration Team at the National Cancer Center, and Kim Ki-ju, a professor at Sungkyunkwan University's School of Social Medicine -- has published the world's first study showing that exposure to air pollution increases the risk of osteoporosis in cancer survivors. (Courtesy of National Cancer Center)

The researchers hypothesized that long-term exposure to air pollution increases osteoporosis risk in cancer survivors.

Using data on air pollution linked to the fourth (2007-2009) and sixth (2015-2021) periods of the National Health and Nutrition Examination Survey, which examined osteoporosis, the researchers analyzed 2,245 cancer survivors and 6,732 healthy people to see if the risk of osteoporosis from air pollution was different in each group.

While no association was observed in healthy people, the researchers found that cancer survivors were at increased risk of osteoporosis with prolonged exposure to fine particulate matter.

Notably, for female cancer survivors, a 4 μg/m3 increase in the average annual concentration of fine particulate matter (PM2.5) was associated with about a 1.25-fold increase in the risk of osteoporosis. An 8 μg/m3 increase in the annual average concentration of PM10 was linked to a 29 percent higher risk of osteoporosis.

“Cancer survivors are at a higher risk of osteoporosis due to fine particulate matter than healthy people, so they should try to lead a lifestyle that minimizes their daily exposure to fine particulate matter,” Professor Kim said.

The study was published in Preventive Medicine, a leading journal in preventive medicine.

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Kim Jung-hyun kjh25@docdocdoc.co.kr

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