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The food and fuel that farms itself

Read time 3 minutes | Tuesday, 1 April 2025

The Takeaway

CSHL Professor Rob Martienssen and colleague Evan Ernst have released new and more accurate genome sequences for five species of duckweed. Their research reveals the specific genes responsible for some of the plant’s most useful traits, allowing for new commercial agriculture applications.

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Under the right conditions, duckweed essentially farms itself. Wastewater, ponds, puddles, swamps—you name it. If there’s enough sunlight and carbon dioxide, the aquatic plant can grow freely. But that’s not all that makes it intriguing. Packed inside duckweed’s tiny fronds is enormous potential as a soil enricher, a fuel source, protein-rich foods, and more. New findings at Cold Spring Harbor Laboratory (CSHL) could help bring all that potential to life.

CSHL Professor and HHMI Investigator Rob Martienssen and Computational Analyst Evan Ernst started working with duckweed over 15 years ago. They see their latest research as one of the most important and eye-opening studies on the plant to date. The team has developed new genome sequences for five duckweed species. The sequences reveal several genes that—when present or absent—may be behind the plant’s unique traits and versatility. Martienssen explains:

“The use of cutting-edge technology allowed us to make a catalog of genes that was extremely accurate. We could tell exactly which genes were there and which were not. A lot of genes that are missing are responsible for features of the plant—open stomata or the lack of roots. We could identify genes that were responsible for each trait.”

Stomata are pores on the surface of plants. They’re crucial for taking in carbon dioxide and releasing oxygen. Open stomata allow for greater intake, making them valuable for carbon capture technology. A lack of roots in some species further increases duckweed’s potential, making it easier for the plant to thrive in any watery environment.

image of duckweed chromosomes

Genes required for chromosomal small RNA are missing in certain duckweed species. This may explain the emergence of vigorous inter-species hybrids with three, rather than two, copies of each chromosome.

Other species possess traits that showcase duckweed’s potential as a food and fuel source. Some traits promote high protein production, allowing for use as animal feed. Others promote starch accumulation, making the plant ripe for biofuel production. Several industries have taken notice. For now, they’re mostly concerned with the duckweed growing in their backyards. Ernst explains:

“Duckweed agriculture is in a nascent stage. Commercial growers are working with different species in the field, evaluating them in their own local situation. There’s so much variation within one species of duckweed—as much as you can find across all the species. So, having multiple genomes for multiple species is critical.”

Martienssen and Ernst hope their genomes will open the door to a new world of commercial applications. That said, their research may tell us as much about the plant’s past. Their study hints at how duckweed split off into different species 59 million years ago. Earth’s climate was quite extreme back then, so duckweed’s genes just might say something about the planet’s future, too.

Written by: Nick Wurm, Communications Specialist | wurm@cshl.edu | 516-367-5940

Funding

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Howard Hughes Medical Institute, U.S. Department of Energy Office of Biological and Environmental Research program, Foundation for Food and Agricultural Research, Seeding Solutions, Rutgers New Jersey Agricultural Experiment Station, Tang Genomics Fund

Citation

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Ernst, E., et al., “Duckweed genomes and epigenomes underlie triploid hybridization and clonal reproduction”, Current Biology, April 1, 2025. DOI: 10.1016/j.cub.2025.03.013

Core Facilites

“The Flow Cytometry Shared Resource offers researchers equipment, training, and assistance with cellular analysis for a variety of applications as well as cell sorting. Our staff oversees equipment maintenance and quality control, trains new users on instrument operation, and assists with assay development and data analysis. We also provide tissue culture facilities for sample preparation and cell maintenance during ongoing flow cytometry experiments.” — Director Pamela Moody

image of the sequencing core facility icon “The Sequencing Technologies and Analysis Shared Resource provides access to an array of high throughput Next Generation Sequencing (NGS) technologies. We offer cutting-edge technology alongside convenient in-house services for a broad range of genetic analysis.” — Project Manager Sara Goodwin, Ph.D.

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The Takeaway

CSHL Professor Rob Martienssen and colleague Evan Ernst have released new and more accurate genome sequences for five species of duckweed. Their research reveals the specific genes responsible for some of the plant’s most useful traits, allowing for new commercial agriculture applications.

Principal Investigator

Rob Martienssen#### Rob Martienssen

Professor & HHMI Investigator

William J. Matheson Professor

Cancer Center Member

Ph.D., Cambridge University, 1986

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