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Endocrine Society Condemns HHS Purge; Lilly Sues Compounders; Obesity Rising in T1D

The Endocrine Society condemned the mass layoffs at HHS, arguing the move "threatens scientific progress that drives our economy and improves the public's health."

Vertex Pharmaceuticals is throwing in the towel on its investigational type 1 diabetes islet cell-device combination VX-264 after it failed to increase C-peptide in a 90-day study.

Eli Lilly sued two mass compounders for selling products containing tirzepatide, the main ingredient in Mounjaro and Zepbound, after the FDA's deadline for copying the injectable had passed. (Reuters)

Combination treatment with a GLP-1 agonist and thiazolidinedione in type 2 diabetes was tied to a significantly lower risk of all-cause mortality, major adverse cardiovascular events, and cardiovascular mortality compared with use of neither of the agents, according to a large cohort study. (JAMA Network Open)

House Democrats are seeking to expand access to gender-affirming care amid a Trump administration crackdown on services. (The Hill)

In a retrospective review of endocrinology telemedicine visits, higher rates of telephone visits, but not video visits, were associated with worse glycemic control in patients with an HbA1c of 8% or higher at baseline. (Journal of Clinical Endocrinology & Metabolism)

A study showed that the prevalence of obesity among youth with type 1 diabetes increased from 2008-2011 to 2020-2023, as did prescriptions for GLP-1 receptor agonists. (Diabetes, Obesity and Metabolism)

NPR looked at how President Trump's executive order to end transgender surgery for minors is affecting patients at a Chicago children's hospital.

Prenatal exposure to per- and polyfluoroalkyl substances (PFAS), a family of endocrine disruptors, may affect long-term maternal insulin resistance and beta cell function, according to follow-up data from the Maternal-Infant Research on Environmental Chemicals study. (Journal of Clinical Endocrinology & Metabolism)

The American College of Physicians and its Council of Subspecialty Societies held a summit to identify barriers to and opportunities for physician education, healthcare policy and care delivery, and addressing weight bias. (Annals of Internal Medicine)

author['full_name']

Kristen Monaco is a senior staff writer, focusing on endocrinology, psychiatry, and nephrology news. Based out of the New York City office, she’s worked at the company since 2015.

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