Edgewise Therapeutics (EWTX) reported positive top-line data of EDG-7500 from the Phase 2 CIRRUS-HCM four-week trial in participants with obstructive or nonobstructive Hypertrophic Cardiomyopathy. EDG-7500 is an oral, selective, cardiac sarcomere modulator, specifically designed to slow early contraction velocity and address impaired cardiac relaxation associated with HCM without impacting systolic function.
The initial data read-out from Part D is expected in the second half of 2025, with Phase 3 initiation planned for the first half of 2026.
Shares of Edgewise Therapeutics are up 9% in pre-market trade on Wednesday.
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