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Serie A Big 5: Who has the toughest start in 2025-26?

ROME, ITALY - MAY 14: Rafael Leao of AC Milan is challenged by Sam Beukema of Bologna during the Coppa Italia Final match between AC Milan and Bologna at Stadio Olimpico on May 14, 2025 in Rome, Italy. (Photo by Marco Rosi/Getty Images)

ROME, ITALY - MAY 14: Rafael Leao of AC Milan is challenged by Sam Beukema of Bologna during the Coppa Italia Final match between AC Milan and Bologna at Stadio Olimpico on May 14, 2025 in Rome, Italy. (Photo by Marco Rosi/Getty Images)

Milan probably have the toughest start to the season among the big five, facing Bologna, Napoli, Juventus, Fiorentina, Atalanta and Roma in the first ten games.

The Serie A fixture list for the 2025-26 campaign was released on Friday.

Football Italia has put down the opening ten games for the big five teams in Italy: Napoli, Inter, Juventus, Roma and Milan and the Rossoneri seem to have the toughest fixture list.

Milan have toughest Serie A start in 2025-26

Juventus coach Massimiliano Allegri before the Italian Serie A football match between Juventus and Fiorentina, at The Allianz Stadium, in Turin on April 7, 2024. (Photo by Marco BERTORELLO / AFP) (Photo by MARCO BERTORELLO/AFP via Getty Images) (Milan target)

Juventus coach Massimiliano Allegri (Photo by Marco BERTORELLO / AFP) (Photo by MARCO BERTORELLO/AFP via Getty Images)

Massimiliano Allegri’s men, in fact, will meet many of their direct rivals in the opening ten games, and the Derby della Madonnina against Inter will come shortly afterwards in Round 12.

Roma haven’t been quite lucky with the draw either, making their debut against Bologna at home, meeting city rivals Lazio in Round 4 and then Fiorentina, Inter and Milan.

Soft Napoli start in 2025-26 Serie A

NAPLES, ITALY - MAY 23: Antonio Conte, Head Coach of Napoli, kisses the Serie A TIM Scudetto title trophy after his team's victory in the Serie A match between Napoli and Cagliari at Stadio Diego Armando Maradona on May 23, 2025 in Naples, Italy. (Photo by Francesco Pecoraro/Getty Images)

NAPLES, ITALY – MAY 23: Antonio Conte, Head Coach of Napoli, kisses the Serie A TIM Scudetto title trophy after his team’s victory in the Serie A match between Napoli and Cagliari at Stadio Diego Armando Maradona on May 23, 2025 in Naples, Italy. (Photo by Francesco Pecoraro/Getty Images)

Defending champions Napoli will face both Milanese sides in the opening ten rounds, as well as Fiorentina away, but they will also encounter two newly promoted teams, Sassuolo and Pisa.

Inter have big games against Juventus, Roma and Napoli as well as Fiorentina, but also matches against Cremonese and Sassuolo coming from Serie B.

Juventus host Atalanta and Milan in consecutive matches in Rounds five and six, but the first big game for them is in Round 3 against Inter, also at the Allianz Stadium.

Napoli **

Sassuolo-Napoli

Napoli-Cagliari

Fiorentina-Napoli

Napoli-Pisa

Milan-Napoli

Napoli-Genoa

Torino-Napoli

Napoli-Inter

Lecce-Napoli

Napoli-Como

Inter ***

Inter vs Torino

Inter vs Udinese

Juventus vs Inter

Inter vs Sassuolo

Cagliari vs Inter

Inter vs Cremonese

Roma vs Inter

Napoli vs Inter

Inter vs Fiorentina

Verona vs Inter

Juventus ***

Juventus-Parma

Genoa-Juventus

Juventus-Inter

Verona-Juventus

Juventus-Atalanta

Juventus-Milan

Como-Juventus

Lazio-Juventus

Juventus-Udinese

Cremonese-Juventus

Roma ****

Roma-Bologna

Pisa-Roma

Roma-Torino

Lazio-Roma

Roma-Verona

Fiorentina-Roma

Roma-Inter

Sassuolo-Roma

Roma-Parma

Milan-Roma

Milan *****

Milan-Cremonese

Lecce-Milan

Milan-Bologna

Udinese-Milan

Milan-Napoli

Juventus-Milan

Milan-Fiorentina

Milan-Pisa

Atalanta-Milan

Milan-Roma

difficulty level from * to *****

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