Jackson missed the 0-0 draw with Crystal Palace last weekend due to suspension, for a red card picked up on the final day of the previous campaign.
Despite available this weekend, Jackson will not be considered for selection due to ongoing opportunities to leave the club during the transfer market.
"He is available, but he is not going to be part of the squad,” Maresca told reporters.
“As we already said, we have two strikers. And also we know that something can happen before the [transfer window](/topic/transfer-window) closes."
Asked if any outgoing or incomings at close, Maresca insisted he was unaware but confirmed that Christopher Nkunku will continue to be left out of contention.
He added: "No idea, to be honest. I prefer to be focused on training sessions and preparing for the game. Christo is with us, but it's the same situation as Nico."