While every season presents it's own challenges, the Buffalo Bills should have no trouble winning these six games in the 2025 season and hopefully capture the franchise's first Super Bowl.
2025 games Bills should have no issue winning
Week 4: Saints @ Bills, September 28th
The Saints still have not named a starting QB after Derek Carr's surprise retirement. It's not looking good for New Orleans, which is between Spencer Rattler and Tyler Shough at the position. Rattler went 0-6 filling in for the injured Carr in 2024, and Shough is an unproven rookie.
Outside of Alvin Kamara, the Saints' offense is young and inexperienced. Buffalo's defense should have its way with New Orleans, especially at home early in the season. Mark this as a W in your calendar.
Week 5: Patriots @ Bills, October 5th (SNF)
New England will probably be better than they were in 2024, but Drake Maye is still young, and going on the road to Buffalo won't be easy for the Patriots. Last year, Buffalo defeated New England 24-21 in a close game, then lost in Week 18 while resting starters. It might be close, but Buffalo should be able to win this game early in the season.
Week 6: Bills @ Falcons, October 13th (MNF)
The Bills go on the road to play the Atlanta Falcons in Week 6, another game that should be an easy win for Buffalo. The Falcons have some talent, but have struggled to put it all together in recent seasons. Michael Penix Jr. has made just three career starts, and he's going to take some time to develop. Don't be surprised if the Bills' defense lays down the hammer in Atlanta.
Week 8: Bills @ Panthers, October 26th
The NFC South will be handing Buffalo plenty of wins in 2025. Carolina is another team in the middle of a rebuild. Bryce Young has a weak supporting cast around him, and the Bills' defense should again feast on an inexperienced Panthers' offense.
Week 16: Bills @ Browns, December 21st
It is impossible to predict which of Cleveland's quarterbacks will be playing by the time Week 16 rolls around in late December. Whoever it is, it probably won't present a challenge to Buffalo. Cleveland is among the weakest teams in the league this year, and the Bills should take advantage.
Week 18: Jets @ Bills, January 4th
The Bills might not need to win by Week 18 if they have already clinched the division. If they do need a win, they have a soft landing this year. Buffalo hosts the New York Jets in Week 18. A year after finishing 5-12 with Aaron Rodgers, the Jets fired their head coach and somehow got even worse under center with the signing of Justin Fields.
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