Man United kick-off their Carabao Cup campaign, travelling across the Pennines to League Two side Grimsby Town's Blundell Park.
United have yet to record a win this season, losing and drawing 1-0 and 1-1 to Arsenal and Fulham respectively.
Rodrigo Muniz gave the Reds their advantage in the second half with an own goal, deflecting **leny yoro'**s effort past **Bernd Leno**before substitute Emile Smith Rowe secured a point for the Cottagers.
Bruno Fernandes missed an early penalty, and after a quiet start to the season, questions are being asked why Kobbie Mainoo is yet to feature this season.
Mainoo has been linked with a possible move away from the club as deadline day nears.
"He is fighting for his position now with Bruno" said Red Devils boss Ruben Amorim
"I changed to two midfielders, I let Mason Mount there because we want to score a goal, and when i change I felt the team needs to return to one holding midfielder near Bruno.
"So he just needs to fight the position with Bruno, like it should be at Manchester United."
Amorim's side were knocked out in the Quarter-finals last year and will look to start their cup campaign positively.
Town have had contrasting fates to their Premier League opposition, starting the season unbeaten with four wins and two draws, including a 3-1 win in their round one fixture as they hosted Shrewsbury Town.
Grimsby were held to a 1-1 draw against Accrington Stanley on Saturday. Jaze Kabia's first half goal was not enough for the Mariners to record their fourth league win of the season.
The Lincolnshire outfit sit fourth, level on points with MK Dons who occupy the final automatic promotion place on goal difference.
This is the first competitive meeting since 1948, 76 years ago for the keen mathematicians reading, with the score ending 1-1.
Manchester United
Noussair Mazraoui is a doubt for this fixture, as he continues to recover from his sustained injury in pre-season, whilst Lisandro Martinez is still some way from a return.
Ruben Amorim is yet to reveal any news surrounding his team selection for this fixture, but it could see the return of Andre Onana as United's keeper of choice.
Rotation is expected to keep every squad member match sharp and refrain from any possible injuries.
Grimsby Town
The hosts have no significant injuries to note, and a strong side is expected as they look to advance to the third round.
Like his counterpart, boss David Artell has not revealed his pre-match thoughts.
Predicted lineup
Manchester United
Onana; Yoro, Maguire, Heaven, Dalot, Leon, Ugarte, Mainoo, Fernandes, Amad, Sesko
Grimsby Town
Pym; Warren, Rodgers, McJannet, Staunton, McEachran, Amaluzor, Turi, Khouri, Burns, Kabia
Key players
Manchester United: Leny Yoro
Yoro has enjoyed life in Manchester since signing last season and has started the season positively, being a bright spark of a Manchester united team who is yet to reach it's real potential.
The French teenager will be pivotal in ensuring Grimsby are not able to cause an upset.
A solid performance against Fulham will give him momentum going into this fixture. The centre back won 100% of his ground duels and recorded five clearances.
Grimsby Town: Jaze Kabia
The Irish forward has already scored four goals this season, with one coming in the first round win.
Despite missing a penalty on Saturday, Kabia scored the opener which was enough to secure a point for the Mariners as they conceded their lead.
The 25-year-old will be pivotal for the hosts as they look to break down a deflated United side.
Match details
Where is the game being played?
Blundell Park, Cleethorpes.
What time is kick-off?
Kick-off is at 20:00 (BST) on Wednesday, 27th August, 2025.
How can I watch?
This fixture is being broadcast live in the United Kingdom on Sky Sports Main Event.