The San Francisco 49ers closed out their 2025 preseason slate at Levi's® Stadium with a 30-23 victory over the Los Angeles Chargers. The game featured plenty of familiar faces on the Chargers sideline, including head coach Jim Harbaugh, quarterback Trey Lance, and 49ers legend turned Chargers linebackers coach NaVorro Bowman. In the preseason finale, it was San Francisco's defense and special teams that made the difference.