Wilson Isidor scored a last-gasp header as Sunderland came from behind to beat Brentford 2-1 at the Stadium of Light.
Dango Ouattara had a goal disallowed for offside in the first half and the visitors' frustrations continued when Kevin Schade's penalty was comfortably saved by Robin Roefs after the break.
A game of few clear-cut chances took a dramatic twist in the final 15 minutes as Igor Thiago's header broke the deadlock, but Enzo Le Fee levelled from the penalty spot five minutes later.
Sunderland continued to push and substitute Isidor nodded home in stoppage-time to snatch three points.
Chelsea 2-0 Fulham
Manchester United 3-2 Burnley
The Black Cats made two changes from their league defeat to Burnley as Le Fee came in alongside Nordi Mukiele, who made his Premier League debut.
Yoane Wissa was still absent for Keith Andrews' side, who named an unchanged team from their league win against Aston Villa and included another start for Jordan Henderson, who made his return to Wearside.
Evanilson's fifth-minute goal earned Bournemouth a deserved 1-0 victory at Tottenham and brought Thomas Frank back down to earth.
Frank had enjoyed an excellent start to life in the Spurs hotseat and followed up last Saturday's excellent win at Manchester City with the purchase of Xavi Simons from RB Leipzig on Friday.
The Danish coach had won seven of his previous 10 meetings with Bournemouth, including two last season, but watched Tottenham produce a tepid display in his fourth match in charge.
Evanilson of Bournemouth scoring against Tottenham, Premier League, August 2023
Evanilson netted early for Bournemouth
Andoni Iraola's side should have won by a greater margin, with David Brooks a constant threat and unfortunate not to score as the Cherries made a mockery of a difficult summer of outgoings with an impressive three points in London.
For Spurs, it shows Frank's squad still needs reinforcements with days of the transfer window left open.
There was a buzz inside Tottenham Hotspur Stadium before kick-off as the crowd awaited the presentation of new €60million signing Simons and a home goal almost followed inside 60 seconds, but Pape Sarr's shot-cum-cross was blocked by Djordje Petrovic.
Jack Grealish continued his excellent start to life at Everton with two more assists in a 3-2 win over troubled Wolves.
The on-loan Manchester City winger created goals for Beto and Kiernan Dewsbury-Hall and was also involved in Iliman Ndiaye's strike as David Moyes' side earned the three points at Molineux.
Grealish, who was left out of Thomas Tuchel's England squad on Friday, has already made four goals for his new club after registering just two Premier League assists in two miserable campaigns at City.
Iliman Ndiaye of Everton (C) after scoring his side's second goal against Wolves, Premier League, August 2025
Iliman Ndiaye netted Everton's second
And he looks like giving Everton the X factor which will keep them away from trouble this season.
Wolves, in contrast, look set for a difficult campaign as they slipped to a third straight defeat.