Max Dowman and Andre Harriman-Annous aren’t involved with the Arsenal U19 squad for their UEFA Youth League game away to Slavia Prague today.
It is anticipated that both players will instead be with the first-team squad for the Champions League fixture against the same opponents tonight.
Dowman, 15, would become the youngest Champions League player ever if was to feature.
Harriman-Annous, 17, is hoping for his second competitive senior appearance after starting against Brighton in the Carabao Cup last week.
Arsenal are without a host of attacking players due to injury, with Viktor Gyokeres, Kai Havertz, Noni Madueke, Gabriel Martinelli and Gabriel Jesus all out.