Our Under-21s' previous fixture was a 2-2 draw, away to Fulham, in Premier League 2.
Shea Lacey scored both goals as the youngsters remain top of the table, with the Cottagers in second place.
There is another high-profile Academy fixture later in the week, when the Under-18s host Derby County in the FA Youth Cup, at Old Trafford, on Friday night.
Both games are being shown live on MUTV.