Helen Bleazard's side will play at Dean Court for the second time this campaign on Sunday, April 11.
It could be a potentially huge game in the context of the season, with the Cherries still firmly in the hunt for promotion despite their defeat to Oxford United last night.
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That leaves Bournemouth in third in the league, but with games in hand over the two sides above them.
Plymouth are four points above the Cherries, but have played 16 games to Bournemouth's 13, while Watford are top of the pile, five points clear of the Dorset team, having played 15.
The Cherries travel to Watford on the final day of the season in what could be a winner-takes-all clash, but they'll be hoping to arrive into that game with some form, and a victory against Bedford at the Vitality Stadium will certainly assist with that.
Tickets for the game, which will kick off at 2pm, will go on sale next week.