Those players not away on international duty will jet out to Murcia on Wednesday for several days of training, with the trip also including a behind-closed-doors friendly against La Liga outfit Elche.
Villa do not play a competitive match until they travel to Bologna for the first leg of a Europa League quarter-final tie on April 9.
And while the extended break does offer boss Unai Emery the chance to give his squad some extra time-off, ahead of the final two months of the campaign, the first week will be busy.
The majority of the Spaniard’s squad, including the likes of skipper John McGinn and England duo Ezri Konsa and Morgan Rogers, are away on international duty until the middle of next week.
Ross Barkley, Ollie Watkins and Tyrone Mings are among the senior players heading out to Spain, while several of the club’s most promising young players are also due to be included in the travelling party.
Villa still have a potential 12 more matches to play in the season’s final two months, seven of them in the Premier League and five in the Europa League, should they go all the way to the final.
Midfield prospect Brad Burrowes, meanwhile, has signed a long-term contract after turning 18 earlier this month.
Burrowes, part of the team which won last season’s FA Youth Cup, made his Premier League debut off the bench in a 3-0 defeat to Crystal Palace last August and has been included in several of the club’s European squads.
Villa academy boss Mark Harrison said: “He is definitely a role model for our younger Academy players.
“We really hope this now provides him with the platform to transition into a senior player at the club.”