Pulisic and McKennie are no strangers to sharing the field, largely because they've been doing so since they were kids. This weekend, of course, is different. This weekend, they're opponents.
There's no overstating how important this game is in the Serie A race. Milan enter the weekend sitting second, with the title well out of reach, as Inter sit 12 points ahead with five games remaining. That puts the focus squarely on earning a Champions League spot for next season.
McKennie and Juventus, meanwhile, have the same aim. They're in fourth at the moment, but just three points behind Milan with a far superior goal difference. A win could vault them all the way up to second. A loss, paired with wins from Como or Roma, would put their fourth-place spot under real threat.
Both sides really need the points. Both players, too, need a good performance. Pulisic will be looking to find the back of the net and silence any doubters about his current form. McKennie, on the other hand, is looking to keep that form going as he builds toward the World Cup.
So, make no mistake, this is the game of the weekend for USMNT fans as two of American soccer's top stars collide in a match with real stakes.