Aston Villa travel on Sunday afternoon, hoping to extend their unbeaten Premier League run and pile more pressure on Manchester United.
The Villains have gone five league matches without defeat, winning three and drawing two, to climb to 10th in the table.
However, Villa must navigate this important clash, with Matty Cash suspended and Aaron Wan-Bissaka facing a late fitness test.
Villa will also be keen to bounce back against Man United after a 3-0 Champions League defeat against Barcelona in midweek.
Match preview
Aston Villa boss Unai Emery has a chance to celebrate his 200th Premier League game in charge with a big win against a struggling Man United side.
Villa have won their last two away league matches and will look to claim another scalp against the hosts.
Man United ended a nine-game winless run in all competitions with a dramatic 3-2 Champions League victory over Roma.
They recovered from two goals down thanks to Bruno Fernandes (from the penalty spot) and Matheus Cunha.
The Brazilian forward then scored a late winner, relieving the pressure on manager Michael Carrick.
That comeback should boost their confidence, but their domestic form remains a concern.
Man United sit 17th in the Premier League and have gone seven league matches without a win.
Villa will look to exploit their weaknesses, particularly if they can make another fast start.
Emery’s side have scored in the first half of each of their last five Premier League games.
Nevertheless, the visitors have defensive issues of their own. They have committed seven errors leading to goals across all competitions this season.
Cutting out individual errors is an area that must improve if they are to leave with three points today.
Match stats
Manchester United have lost only two of their 31 home Premier League meetings with Aston Villa, winning 24 and drawing five.
Villa have won just one of their last seven Premier League encounters with Man United under Emery, drawing one and losing five.
However, their recent away form is encouraging, with consecutive league victories after just two wins in their previous 12 away matches.
Nicolas Jackson has scored five goals in eight Premier League appearances for Villa.
Aston Villa team news
Emery must make changes to his defence, with Cash suspended after accumulating five yellow cards and Matteo Ruggeri sidelined by injury.
Aaron Wan-Bissaka is close to returning after recovering from a hamstring problem.
Still, the former Manchester United defender faces a late fitness test before a potential return to Old Trafford.
If he is not ready to start, ‘Mr reliable‘ Lamare Bogarde is expected to deputise at right-back, with Ian Maatsen filling the opposite flank.
Amadou Onana remains some way from returning as he continues his recovery from an anterior cruciate ligament injury.
Aston Villa predicted XI (4-2-3-1)
Zion Suzuki; Lamare Bogarde, Victor Lindelof, Pau Torres, Ian Maatsen; Boubacar Kamara, Joao Gomes; Emiliano Buendia, John McGinn, Johan Manzambi; Nicolas Jackson.